Results for 'A. Keith Dunker'

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  1.  49
    Close encounters of the third kind: disordered domains and the interactions of proteins.Peter Tompa, Monika Fuxreiter, Christopher J. Oldfield, Istvan Simon, A. Keith Dunker & Vladimir N. Uversky - 2009 - Bioessays 31 (3):328-335.
    Protein–protein interactions are thought to be mediated by domains, which are autonomous folding units of proteins. Recently, a second type of interaction has been suggested, mediated by short segments termed linear motifs, which are related to recognition elements of intrinsically disordered regions. Here, we propose a third kind of protein–protein recognition mechanism, mediated by disordered regions longer than 20–30 residues. Bioinformatics predictions and well‐characterized examples, such as the kinase‐inhibitory domain of Cdk inhibitors and the Wiskott–Aldrich syndrome protein (WASP)‐homology domain 2 (...)
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  2.  18
    Close encounters of the third kind: disordered domains and the interactions of proteins.Peter Tompa, Monika Fuxreiter, Christopher J. Oldfield, Istvan Simon, A. Keith Dunker & Vladimir N. Uversky - 2009 - Bioessays 31 (3):328-335.
    Protein–protein interactions are thought to be mediated by domains, which are autonomous folding units of proteins. Recently, a second type of interaction has been suggested, mediated by short segments termed linear motifs, which are related to recognition elements of intrinsically disordered regions. Here, we propose a third kind of protein–protein recognition mechanism, mediated by disordered regions longer than 20–30 residues. Bioinformatics predictions and well‐characterized examples, such as the kinase‐inhibitory domain of Cdk inhibitors and the Wiskott–Aldrich syndrome protein (WASP)‐homology domain 2 (...)
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  3.  22
    Explaining the origins of multicellularity: between evolutionary dynamics and developmental mechanisms.A. C. Love - 2016 - In K. J. Niklas & S. A. Newman (eds.), Multicellularity: Origins and Evolution. MIT press. pp. 279–295.
    Overview The evolution of multicellularity raises questions regarding genomic and developmental commonalities and discordances, selective advantages and disadvantages, physical determinants of development, and the origins of morphological novelties. It also represents a change in the definition of individuality, because a new organism emerges from interactions among single cells. This volume considers these and other questions, with contributions that explore the origins and consequences of the evolution of multicellularity, addressing a range of topics, organisms, and experimental protocols. Each section focuses on (...)
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  4.  30
    An empirical analysis of free-recall to paired-associate transfer.A. Keith Barton - 1973 - Journal of Experimental Psychology 97 (1):79.
  5.  26
    Picture versus word and relevant value "Relatedness" in rule-learning problems.A. Keith Barton - 1972 - Journal of Experimental Psychology 96 (1):208.
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  6.  28
    Transfer from free-recall to paired-associate learning.A. Keith Barton & Robert K. Young - 1972 - Journal of Experimental Psychology 95 (1):240.
  7.  12
    The objects of action and perception.Melvyn A. Goodale & G. Keith Humphrey - 1998 - Cognition 67 (1-2):181-207.
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  8.  22
    Pragmatist and American Philosophical Perspectives on Resilience.Kelly A. Parker & Heather E. Keith (eds.) - 2019 - Lanham, Maryland: Lexington Books.
    From cultural figures such as Benjamin Franklin and Wendell Berry to philosophers such as Jane Addams and William James, this collection explores the usefulness of theoretical work in American philosophy and pragmatism to resilience practices in ecology, community, rurality, and psychology.
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  9.  8
    Manipulated retrievability in free recall.Robert K. Young & A. Keith Barton - 1972 - Journal of Experimental Psychology 93 (1):143.
  10.  16
    The Politics and Ethics of Contemporary Work: Whither Work?Keith Breen (ed.) - 2021 - Routledge.
    Bringing together leading international scholars within the fields of social and political theory and philosophy, this book explores how we should understand work and its role in our lives and wider society. What challenges are posed by work in our changing economy and the new economic forms that are beginning to emerge, and how can we best address these challenges? In what ways do patterns of working, as well as work technologies, shape people's lives within and outside work, in particular (...)
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  11.  26
    Scientific Genius: A Psychology of Science.John Ziman & Dean Keith Simonton - 1989 - British Journal of Educational Studies 37 (3):299.
  12.  69
    Philosophy and Common Sense.Keith Campbell - 1988 - Philosophy 63 (244):161 - 174.
    This paper identifies moore's use of a carefully selected group of propositions from common sense as a touchstone for philosophical credibility, As belonging to a tradition in metaphysics which is neither ambitiously constructive nor sceptically negative, But rather acts as a "whistle-Blowing" restraint. It traces the later disappearance of any common-Sensical touchstones, Then argues that two aspects of fodor's "modularity of mind" provide a basis for the return of a modest reliance on common-Sense knowledge as a point of reference. The (...)
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  13.  70
    Descartes, La Mettrie, Language, and Machines.Keith Gunderson - 1964 - Philosophy 39 (149):193 - 222.
    IN L'Homme machine La Mettrie at one point discusses the possibility of teaching an ape to speak, and later he suggests that just as the inventor Vaucanson had made a mechanical flute player and a mechanical duck, it might be possible some day for ‘another Prometheus’ to make a mechanical man which could talk.
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  14.  75
    Aquinas on Attachment, Envy, and Hatred in the "Summa Theologica".Keith Green - 2007 - Journal of Religious Ethics 35 (3):403 - 428.
    This essay examines Aquinas's discussions of hatred in Summa Theologica I-II, Q. 29 and II-II, Q. 34, in order to retrieve an account of what contemporary theorists of the emotions call its cognitive contents. In Aquinas's view, hatred is constituted as a passion by a narrative pattern that includes its intentional object, beliefs, perceptions of changes in bodily states, and motivated desires. This essay endorses Aquinas's broadly "cognitivist" account of passional hatred, in line with his way of treating passions in (...)
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  15.  73
    Met aknowledge: Undefeated justification.Keith Lehrer - 1988 - Synthese 74 (3):329 - 347.
    Internalism and externalism are both false. What is needed to convert true belief into knowledge is the appropriate blend of subjective and objective factors to yield the appropriate sort of connection between mind and the world. The sort of knowledge explicated is calledmetaknowledge and is knowledge that involves the evaluation of incoming information in terms of a background system. It is proposed that knowledge is equivalent to undefeated justification which is justification on the basis of every system that eliminates or (...)
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  16.  38
    Genetic Research as Therapy: Implications of "Gene Therapy" for Informed Consent.Larry R. Churchill, Myra L. Collins, Nancy M. R. King, Stephen G. Pemberton & Keith A. Wailoo - 1998 - Journal of Law, Medicine and Ethics 26 (1):38-47.
    In March 1996, the General Accounting Office (GAO) issued the reportScientific Research: Continued Vigilance Critical to Protecting Human Subjects.It stated that “an inherent conflict of interest exists when physician-researchers include their patients in research protocols. If the physicians do not clearly distinguish between research and treatment in their attempt to inform subjects, the possible benefits of a study can be overemphasized and the risks minimized.” The report also acknowledged that “the line between research and treatment is not always cleartoclinicians. Controversy (...)
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  17.  18
    Biased attention retraining in dysphoria: a failure to replicate.Liza Mastikhina & Keith Dobson - 2017 - Cognition and Emotion 31 (3).
  18. A note on prediction and deduction.John Canfield & Keith Lehrer - 1961 - Philosophy of Science 28 (2):204-208.
    This paper argues against the deductive reconstruction of scientific prediction, that is, against the view that in prediction the predicted event follows deductively from the laws and initial conditions that are the basis of the prediction. The major argument of the paper is intended to show that the deductive reconstruction is an inaccurate reconstruction of actual scientific procedure. Our reason for maintaining that it is inaccurate is that if the deductive reconstruction were an accurate reconstruction, then scientific prediction would be (...)
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  19.  28
    RePAIR consensus guidelines: Responsibilities of Publishers, Agencies, Institutions, and Researchers in protecting the integrity of the research record.Alice Young, B. R. Woods, Tamara Welschot, Dan Wainstock, Kaoru Sakabe, Kenneth D. Pimple, Charon A. Pierson, Kelly Perry, Jennifer K. Nyborg, Barb Houser, Anna Keith, Ferric Fang, Arthur M. Buchberg, Lyndon Branfield, Monica Bradford, Catherine Bens, Jeffrey Beall, Laura Bandura-Morgan, Noémie Aubert Bonn & Carolyn J. Broccardo - 2018 - Research Integrity and Peer Review 3 (1).
    The progression of research and scholarly inquiry does not occur in isolation and is wholly dependent on accurate reporting of methods and results, and successful replication of prior work. Without mechanisms to correct the literature, much time and money is wasted on research based on a crumbling foundation. These guidelines serve to outline the respective responsibilities of researchers, institutions, agencies, and publishers or editors in maintaining the integrity of the research record. Delineating these complementary roles and proposing solutions for common (...)
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  20.  27
    Creative productivity: A predictive and explanatory model of career trajectories and landmarks.Dean Keith Simonton - 1997 - Psychological Review 104 (1):66-89.
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  21.  5
    Rationality.Keith Lehrer - 1999 - In John Greco & Ernest Sosa (eds.), The Blackwell Guide to Epistemology. Malden, Mass.: Wiley-Blackwell. pp. 206–219.
    Man is a rational animal, or so says Aristotle.1 But what is rationality? It is the use of reason to reach a certain level of reasonableness or unreasonableness. To be rational is to be extremely reasonable as to be irrational is to be extremely unreasonable. The varieties of rationality and distinctions about rationality are many. First of all, there is a distinction between practical and theoretical rationality. Secondly, there is a distinction between synchronic or static rationality and diachronic or dynamic (...)
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  22.  25
    Reid on Testimony and Perception.Keith Lehrer & John-Christian Smith - 1985 - Canadian Journal of Philosophy 15 (sup1):21-38.
    Reid defended common sense against scepticism by appeal to the claim that our faculties should be considered trustworthy until some argument proves them to be untrustworthy. He believed, of course, that no such argument would be forthcoming. In this paper, we shall investigate Reid's defense of the faculty of perception and the evidence of the senses by analogy with the faculty of language and the evidence of testimony. Reid argued that the evidence of testimony should be trusted unless there is (...)
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  23.  48
    Consciousness AND REGRESS.Keith Lehrer - 2008 - Journal of Scottish Philosophy 6 (1):45-57.
    Thomas Reid has a theory of consciousness that is central to his philosophy of mind but which raises a regress problem. I have two tasks in this paper. The first is to give an account of Reid's views on consciousness and the avoidance of the regress based on textual analysis. The second is to expand the theory of consciousness Reid gives to offer a deeper explanation of how the regress is avoided that is based on Reid's philosophy of mind but (...)
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  24.  45
    Rape: A Philosophical Investigation.Keith Burgess-Jackson - 1996 - Dartmouth Publishing Company.
    This is the first book-length philosophical examination of rape, which has received ample attention from feminists, legal scholars and social scientists.
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  25.  42
    Book Reviews Section 1.D. Bob Gowin, Jerry B. Burnell, Pat Keith, Jaw-Woei Chiou, Kermit J. Blank, George Willis, George Kincaid, Lawrence D. Klein, James A. Nathan, Houston M. Burnside, Daniel P. Hudin, Erwin H. Epstein, Ivan L. Barrientos, Darrell S. Willey, Mathew Zachariah, Robert H. Beck & Edward R. Beauchamp - 1973 - Educational Studies 4 (3):134-145.
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  26. Atomism and Semantics in the Philosophy of Jerrold Katz.Keith Begley - 2020 - In Ugo Zilioli (ed.), Atomism in Philosophy: A History from Antiquity to the Present. New York: Bloomsbury Academic. pp. 312-330.
    Jerrold J. Katz often explained his semantic theory by way of an analogy with physical atomism and an attendant analogy with chemistry. In this chapter, I track the origin and uses of these analogies by Katz, both in explaining and defending his decompositional semantic theory, through the various phases of his work throughout his career.
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  27.  63
    Coherence and the Truth Connection.Keith Lehrer - 2005 - Erkenntnis 63 (3):413-423.
    There is an objection to coherence theories of knowledge to the effect that coherence is not connected with truth, so that when coherence leads to truth this is just a matter of luck. Coherence theories embrace falliblism, to be sure, but that does not sustain the objection. Coherence is connected with truth by principles of justified acceptance that explain the connection between coherence and truth. Coherence is connected with truth by explanatory principle, not just luck.
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  28.  9
    Red flags in psychotherapy: stories of ethics complaints and resolutions.Patricia Keith-Spiegel - 2014 - New York: Routledge, Taylor & Francis Group.
    Preface : how and why the stories came to be -- Introduction : self-deception and red flags -- Sammy meets the wolf : meet the characters who will decide the cases -- I'm not your monkey : loss of control with a difficult client -- Junk yard therapy : self-delusion and exploitation -- Rats! : warring colleagues -- The John : a predator at work and play -- The raid on Hollywood Boulevard : the professional role vs. the right to (...)
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  29.  43
    A solution to the binding problem for compositional connectionism.John E. Hummel, Keith J. Holyoak, Collin Green, Leonidas Aa Doumas, Derek Devnich, Aniket Kittur & Donald J. Kalar - 2004 - In Simon D. Levy & Ross Gayler (eds.), Compositional Connectionism in Cognitive Science. AAAI Press.
  30.  46
    Reply to Fumerton.Keith Lehrer - 2002 - Philosophy and Phenomenological Research 64 (2):436-438.
    It is a pleasure to have the opportunity to reply to such a distinguished critic as Richard Fumerton and to clarify both my position and why I am reluctant to accept the alternative account of direct awareness Fumerton offers to us. Here are my replies. First of all, Fumerton says that the problem of representation is the problem of accounting for the security from error of self-presenting states. That is not the problem of representation I was concerned with in my (...)
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  31.  86
    Schlick and Neurath.Keith Lehrer - 1982 - Grazer Philosophische Studien 16 (1):49-61.
    Schlick and Neurath shared a common assumption, what I call the verification theory of truth, as well as the verification of meaning. It is the claim that the truth of a sentence is the method of it's verification. For Neurath, the method of scientific verification must be interpersonal, and, therefore, private experience is precluded. This leads hmi to the doctrme that there is no truth beyond intersubjective agreement. Schlick, on the contrary, regarded it as obvious that certain sentences, even if (...)
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  32.  16
    A decision-by-sampling account of decision under risk.Neil Stewart & Keith Simpson - 2008 - In Nick Chater & Mike Oaksford (eds.), The Probabilistic Mind: Prospects for Bayesian Cognitive Science. Oxford University Press. pp. 261--276.
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  33.  19
    The Unity of the Manifest and Scientific Image by Self-Representation.Keith Lehrer - 2012 - Humana Mente 5 (21).
    Sellars distinguished in Empiricism and Philosophy of Mind between ordinary discourse, which expressed his “manifest image”, and scientific discourse, which articulated his “scientific image” of man-in-the-world in a way that is both central and problematic to the rest of his philosophy. Our contention is that the problematic feature of the distinction results from Sellars theory of inner episodes as theoretical entities. On the other hand, as Sellars attempted to account for our noninferential knowledge of such states, particularly in correspondence with (...)
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  34.  21
    Smells, exemplars and evidence: smelling knowledge of the external world.Keith Lehrer - 2018 - Inquiry: An Interdisciplinary Journal of Philosophy 61 (5-6):611-631.
    Conscious experience of the sensation of smell provides exemplars of the sensation exhibiting to us what it is like. These exemplars of experiences can become vehicles or terms of representation and meaning. I call this exemplar representation and the process exemplarization. The notion of exemplarization is indebted to Hume and Goodman. I modify the notion here to apply to the sensation of smell. Exemplar representation differs from verbal representation because the exemplar, like a sample, exhibits what the represented items smell (...)
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  35.  40
    The Non-Epistemic Explanation of Religious Belief.Keith E. Yandell - 1990 - International Journal for Philosophy of Religion 27 (1/2):87 - 120.
    The preceding two sections have considered, respectively, the discreditation of psychological belief, and of propositional belief, which begins with the claim that a belief possessed by some person is non-epistemically explicable and ends with the claim that that person is unreasonable or that that belief is (probably) false. Obviously, only certain strategies of discreditation were discussed, and those only partially. But if the examples of discrediting strategies were representative, and the remarks made about them were correct, what, if anything, follows?It (...)
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  36.  22
    Argument practices.William Keith - 1995 - Argumentation 9 (1):163-179.
    The move to Postmodernism in argumentation is often predicated on the rejection of the formal basis of argument in logic. While this rejection may be justified, and is widely discussed in the literature, the loss of logic creates problems that a Postmodern theory of argument must address without recourse to logic and its attendant modernist assumptions. This essay argues that conceiving of argument in terms ofpractices will address the key problematics of Postmodernism without abandoning those features of argumentation that make (...)
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  37.  22
    Beyond the Legend: Uncovering the Historical Circumstances Behind the Rescue of the Danish Jews.Ellen Keith - 2010 - Constellations (University of Alberta Student Journal) 2 (1).
    Denmark is one of the only European countries that can speak of its involvement in the Holocaust with some sense of pride. In October of 1943, the Danes pulled off a substantial rescue mission during which they led the majority of the Danish Jews to safety in Sweden. Traditional representations of this event attribute its success to the outstanding moral character of the Danes. This paper challenges this popular view and explores a variety of factors which together facilitated the rescue (...)
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  38.  72
    Autonomic and EEG patterns during eyes-closed rest and transcendental meditation (TM) practice: The basis for a neural model of TM practice.Frederick Travis & R. Keith Wallace - 1999 - Consciousness and Cognition 8 (3):302-318.
    In this single-blind within-subject study, autonomic and EEG variables were compared during 10-min, order-balanced eyes-closed rest and Transcendental Meditation (TM) sessions. TM sessions were distinguished by (1) lower breath rates, (2) lower skin conductance levels, (3) higher respiratory sinus arrhythmia levels, and (4) higher alpha anterior-posterior and frontal EEG coherence. Alpha power was not significantly different between conditions. These results were seen in the first minute and were maintained throughout the 10-min sessions. TM practice appears to (1) lead to a (...)
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  39. A Fourteenth-Century Picard Translation-Commentary of the «Consolatio Philosophiae».J. Keith Atkinson - 1987 - In Alastair J. Minnis (ed.), The Medieval Boethius: Studies in the Vernacular Translations of De Consolatione Philosophiae. D.S. Brewer. pp. 32--62.
     
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  40.  51
    Bergson and philosophy as a way of life.Keith Ansell-Pearson - 2020 - In Alexandre Lefebvre & Nils F. Schott (eds.), Interpreting Bergson: Critical Essays. Cambridge: Cambridge University Press. pp. 121-138.
    The chapter presents Bergson’s conception of philosophy as a way of life, as a thinking that seeks to make contact with the creativity of life as a whole. This endeavor to alter our vision of the world, and ultimately, our action and sense of being in the world, seeks to operate a “conversion of attention.” For Bergson, such a conversion is tied in with what he calls the “true empiricism” that allows us to experience and think change as that which (...)
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  41. Nietzsche: A radical challenge to political theory.Keith Ansell-Pearson - 1990 - Radical Philosophy 54 (Spring):10-18.
  42. The Mind Bursary.Frank Cioffi Obscurantism, G. A. Equality, Keith Graham, Peter Carruthers, Cynthia MacDonald, Paul Snowden, Howard Robinson, David Over, Paul Guyer & Ralph Walker - 1990 - Mind 99:394.
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  43.  42
    The physiology of desire.Keith Butler - 1992 - Journal of Mind and Behavior 13 (1):69-88.
    I argue, contrary to wide-spread opinion, that belief-desire psychology is likely to reduce smoothly to neuroscientific theory. I therefore reject P.M. Churchland's eliminativism and Fodor's nonreductive materialism. The case for this claim consists in an example reduction of the desire construct to a suitable construct in neuroscience. A brief account of the standard view of intertheoretic reduction is provided at the outset. An analysis of the desire construct in belief-desire psychology is then undertaken. Armed with these tools, the paper moves (...)
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  44.  18
    Critical Trends in Interpreting Sulpicia.Alison Keith - 2006 - Classical World: A Quarterly Journal on Antiquity 100 (1):3-10.
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  45.  8
    Imperial Geographies in Tibullan Elegy.Alison Keith - 2014 - Classical World: A Quarterly Journal on Antiquity 107 (4):477-492.
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  46.  20
    Abnormal frontostriatal activity in recently abstinent cocaine users during implicit moral processing.Brendan M. Caldwell, Carla L. Harenski, Keith A. Harenski, Samantha J. Fede, Vaughn R. Steele, Michael R. Koenigs & Kent A. Kiehl - 2015 - Frontiers in Human Neuroscience 9:155442.
    Investigations into the neurobiology of moral cognition are often done by examining clinical populations characterized by diminished moral emotions and a proclivity toward immoral behavior. Psychopathy is the most common disorder studied for this purpose. Although cocaine abuse is highly co-morbid with psychopathy and cocaine-dependent individuals exhibit many of the same abnormalities in socio-affective processing as psychopaths, this population has received relatively little attention in moral psychology. To address this issue, the authors used functional magnetic resonance imaging (fMRI) to record (...)
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  47.  14
    Politics of Practical Reasoning: Integrating Action, Discourse and Argument.Keith Breen, Frank Canavan, Gerard Casey, Heike Felzmann, Thomas Gil, Karsten Harries, Richard Hull, Sebastian Lalla, Elizabeth Langhorne, Thomas Nisters, Felix O'Murchadha & Fran O'Rourke (eds.) - 2012 - Lexington Books.
    This book treats practical and political reasoning as an active engagement with the world and other people; it cannot be understood as exclusively cognitive and this is seen as a virtue rather than a deficiency. Informal, emotional, characterological, aesthetic and interactional aspects of thought can be constituents of reasonable arguing. The work examines key capacities connected with argumentation, in a variety of fields from professional and medical ethics to work organization and the practice of art.
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  48.  49
    No Will to Know: The Rise and Fall of African Civil Registration in Twentieth-Century South Africa.Keith Breckenridge - 2012 - In Keith Breckenridge & Simon Szreter (eds.), Registration and Recognition: Documenting the Person in World History. OUP/British Academy. pp. 357-383.
    Vital statistics have been politically fraught in South Africa for decades, not least because the state made very little effort to record information about the well-being of African women and children. This chapter shows that in the last years of the nineteenth century a working system of vital registration was developed in the colony of Natal and in the native reserves of the Transkei. From the beginning this delegated bureaucracy faced opposition from African patriarchs, from parsimonious white elected leaders and (...)
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  49.  10
    Mammalian DNA single‐strand break repair: an X‐ra(y)ted affair.Keith W. Caldecott - 2001 - Bioessays 23 (5):447-455.
    The genetic stability of living cells is continuously threatened by the presence of endogenous reactive oxygen species and other genotoxic molecules. Of particular threat are the thousands of DNA single-strand breaks that arise in each cell, each day, both directly from disintegration of damaged sugars and indirectly from the excision repair of damaged bases. If un-repaired, single-strand breaks can be converted into double-strand breaks during DNA replication, potentially resulting in chromosomal rearrangement and genetic deletion. Consequently, cells have adopted multiple pathways (...)
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  50.  6
    Ethics and Politics in Seventeenth Century France.Keith Cameron & Elizabeth Woodrough (eds.) - 1996 - University of Exeter Press.
    This collection of twenty essays, of which five are in French, written by leading English and French literary and historical scholars, deconstructs the ethical and political framework supporting and circumscribing the actions of a powerful elite in France between the early 1600s and the final years of Louis XIV's reign. Reflecting a diversity of individual concerns, the essays, which offer a radical double questioning of the absolute values in which were founded the authority of Church, King and nobility, have been (...)
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